Factor XIII Val34Leu polymorphism, factor XIII antigen levels and activity and the risk of deep venous thrombosis
نویسندگان
چکیده
منابع مشابه
Factor XIII val34leu and the risk of myocardial infarction.
BACKGROUND AND OBJECTIVE Recent studies have suggested an association between a genetic variation in the coagulation factor XIII (FXIII Val34Leu) and decreased risk of vascular thrombosis. DESIGN AND METHODS We investigated the frequency of the FXIII Val34Leu polymorphism in 150 consecutive, unrelated and relatively young (<55 years) survivors of myocardial infarction (MI) with angiographical...
متن کاملFactor XIII Val34Leu polymorphism in patients with cardiac syndrome X.
BACKGROUND The aim of the study was to examine the frequency of factor XIII polymorphism among patients with cardiac syndrome X (CSX). METHODS This study was designed as a cross-sectional and observational study. Forty-eight female patients with CSX and 36 controls matched by age, gender, diabetes, and hypertension were studied. CSX was defined as typical chest pain during rest or effort, abn...
متن کاملRole of factor XIII Val34Leu polymorphism in retinal artery occlusion.
BACKGROUND AND PURPOSE Factor XIII (FXIII) Val34Leu, a common polymorphism in the gene for factor XIII, has been associated with a lower risk of stroke, myocardial infarction, and deep vein thrombosis. Ineffective fibrin cross-linking has been suggested to be causative. The aim of the present case-control study was to investigate the role of FXIII Val34Leu polymorphism in patients with retinal ...
متن کاملFactor XIII Val34Leu polymorphism in primary intracerebral haemorrhage.
INTRODUCTION Recently, the common Val34Leu polymorphism of the A-chain factor XIII gene, associated with high factor XIII activity, has been identified as a protective genetic factor against occlusive arterial and venous diseases. Moreover, this polymorphism has been suggested to be the first one to increase the risk of cerebral haemorrhage in a small number of Caucasian patients. The aim of ou...
متن کاملPrevalence of Factor Xiii Val34leu Polymorphism in Thrombosis Cases in the Southeast of Turkey and Its Correlation with Thrombosis
Factor XIII (Fibrin-stabilizing factor) is a tetrameric structural pro-transglutaminase from the transglutaminase family. Factor XIII activity is associated with the structure of fibrin clot. Factor XIII turns into XIII-A, which is an active transglutaminase, in the result phase of coagulation cascade together with Ca and thrombin activation. The main aim of Factor XIIIA is to connect ε(δ-gluta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2002
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2002.03797.x